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CENTENNIAL, Colo., June 1,
2006 -Cell>Point today announced it plans to start a Phase II
clinical trial to evaluate the effectiveness of its 99mTc-EC-DG
(Technetium-99m-Ethylenedicys-teine-Deoxyglucose) in diagnosing the
presence of viable tissue in regions of the myocardium damaged by
myocardial infarction or chronic coronary artery disease.
The company has completed the Phase I safety trial on
99mTc-EC-DG in addition to canine heart remodeling studies.
Previously developed as a functional imaging agent for
oncology applications, 99m Tc-EC-DG should improve diagnostic accuracy
in determining if a patient would benefit from coronary
revascularization, Cell>Point believes, whether in the setting of the
cardiologist's practice or hospital emergency room. The sooner the
diagnosis is confirmed, the better chance a patient will have for
improved systolic function following a myocardial infarction.
In addition to myocardial viability, Cell>Point plans to study the
effectiveness of 99mTc-EC-DG in other cardiac indications including a
study in conjunction with myocardial perfusion imaging in women (who
often exhibit false-positive results following the perfusion stress
procedure), and a study of early diagnosis of congestive heart failure
onset.
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